Key Benefits

• Ashwagandha root extract 500mg per capsule Withania somnifera, root | 4:1 extract | QCE 2,000mg per capsule | QCE 4,000mg per daily dose
• Rasayana (Rejuvenative Tonic) Traditional Ayurvedic use | Health Canada licensed NPN 80062481
• Relieves general debility, especially during convalescence or old age Licensed use NPN 80062481
• Only 1 non medicinal ingredient Hypromellose (vegetable capsule shell). Nothing else
• Vegan capsule Hypromellose shell, no gelatin
• Non GMO | Gluten free | No artificial ingredients
• Made in Canada GMP certified facility under Health Canada oversight
• 60 capsules At 2 capsules per day

What This Is

Ashwagandha 500mg provides 500mg of Withania somnifera root extract (4:1, QCE 2,000mg) per vegan capsule. At the recommended dose of 2 capsules once daily, each daily serving provides 1,000mg of extract equivalent to 4,000mg of dried ashwagandha root. One non medicinal ingredient: hypromellose vegetable capsule shell. Licensed by Health Canada with NPN 80062481 for traditional Ayurvedic use as Rasayana (Rejuvenative Tonic) and to relieve general debility, especially during convalescence or old age. Manufactured in Canada to GMP standards under the Nutridom brand.

The Science

What Is Ashwagandha?

Withania somnifera (Solanaceae family) is a medicinal plant native to India, North Africa, and the Mediterranean. Somnifera means sleep-inducing in Latin. Ashwagandha comes from Sanskrit: ashwa (horse) and gandha (smell), reflecting the traditional belief that it confers the strength and vitality of a horse. Also known as Indian ginseng and winter cherry. Ashwagandha has been used in Ayurvedic medicine for over 3,000 years as one of the most important Rasayana herbs, used to promote rejuvenation, vitality, and resilience.

Rasayana and General Debility: The Licensed Uses

Rasayana is one of the eight branches of Ayurveda, meaning path of essence: herbs used to promote rejuvenation, vitality, and resilience. General debility is a state of weakness or lack of vitality. Convalescence is the recovery period following illness, surgery, or prolonged stress. Ashwagandha has been used in Ayurvedic practice for centuries to support the body's return to strength during and after periods of depletion. These are the Health Canada licensed uses for NPN 80062481 and are the licensed, verifiable claims for this product.

The Bioactive Compounds: Withanolides

Withanolides are the primary bioactive compounds in ashwagandha root: ergostane-type steroidal lactones unique to the Withania genus. The most studied is withaferin A. Withanolides work through two primary mechanisms relevant to the licensed uses of this formula.

HPA Axis Modulation

The HPA (hypothalamic-pituitary-adrenal) axis is the body's primary stress response system. Chronic stress dysregulates this axis, leading to sustained elevated cortisol output. Withanolides modulate the HPA axis, supporting normalization of cortisol output. This is the primary mechanism underlying ashwagandha's Rasayana and general debility uses in Ayurvedic medicine.

GABA-Mimetic Activity

Ashwagandha compounds interact with GABA-A receptors, the primary inhibitory receptors in the central nervous system. This contributes to its calming properties and is the pharmacological basis for the caution against combining ashwagandha with alcohol or sedative drugs: the effects on the central nervous system can be additive.

Understanding 4:1 Extract and QCE

A 4:1 extract ratio means 4 parts of dried ashwagandha root are used to produce 1 part of finished extract, concentrating the withanolides to approximately four times their concentration in dried root powder. The quantity crude equivalent (QCE) of 2,000mg is the amount of crude dried root the extract in each capsule is equivalent to, expressed as a Health Canada standardized labelling figure. The actual extract content per capsule is 500mg. At 2 capsules per day, the daily dose provides 1,000mg of extract equivalent to 4,000mg of dried ashwagandha root.

Medicinal Ingredient (per capsule)

• Ashwagandha (Withania somnifera, root) 500mg 4:1 extract | QCE 2,000mg | Rasayana (Rejuvenative Tonic) | Relieves general debility especially during convalescence or old age | NPN 80062481

Non medicinal ingredient: Hypromellose (vegetable capsule shell).

Quality and Trust

• NPN 80062481 Licensed by Health Canada as a Natural Health Product
• Made in Canada GMP certified facility under Health Canada oversight
• 4:1 root extract 500mg per capsule | QCE 2,000mg per capsule | QCE 4,000mg per daily dose
• Only 1 non medicinal ingredient Hypromellose vegetable capsule shell
• Vegan capsule Hypromellose shell, no gelatin
• Non GMO | Gluten free | No artificial ingredients
• 60 capsules At 2 capsules per day

Who This Is For

• Adults (not pregnant or breastfeeding) seeking a traditional Ayurvedic Rasayana (Rejuvenative Tonic) for vitality and general wellbeing from a Health Canada licensed formula
• Those experiencing general debility, fatigue, or weakness during or after illness, surgery, or prolonged stress (convalescence), consistent with the licensed use of NPN 80062481
• Those who want a single ingredient, clean label ashwagandha formula with only 1 non medicinal ingredient
• Health conscious consumers who prefer a Health Canada licensed, GMP manufactured, vegan, Canadian made ashwagandha supplement

How to Use

Adults: Take 2 capsules once daily. Consumption with alcohol, other drugs, or natural health products with sedative properties is not recommended. Not recommended for pregnant or breastfeeding women.

Safety and Cautions

Not recommended for pregnant or breastfeeding women. Consumption with alcohol, other drugs, or natural health products with sedative properties is not recommended. Consult a healthcare practitioner before use if you are taking medications or have a pre-existing medical condition. Keep out of reach of children. Store in a cool, dry place away from direct sunlight and moisture. Do not use if the seal is broken or missing.

NPN 80062481. This product is not intended to diagnose, treat, cure, or prevent any disease. All health claims are consistent with Health Canada's Natural Health Products Regulations.