Key Benefits

• Biotin 10,000mcg per capsule Vitamin B7 | High potency water soluble B vitamin
• Factor in the maintenance of good health Health Canada licensed NPN 80071632
• Helps metabolize carbohydrates, fats, and proteins Licensed use NPN 80071632
• Vegan capsule Hypromellose shell, no gelatin
• Non GMO | Gluten free | Soy free | Dairy free
• Made in Canada GMP certified facility under Health Canada oversight
• 60 capsules 60 day supply at 1 capsule per day

What This Is

Biotin 10,000mcg provides high potency biotin (vitamin B7) at 10,000mcg per vegan capsule. Biotin is a water soluble B vitamin that functions as an essential cofactor for carboxylase enzymes involved in the metabolism of carbohydrates, fats, and proteins. This formula is licensed by Health Canada with NPN 80071632, manufactured in Canada to GMP standards under the Nutridom brand.

This product is intended for proactive wellness support and is not a substitute for medical care. Consult a healthcare practitioner for use beyond 4 weeks.

The Science

What Is Biotin (Vitamin B7)?

Biotin (vitamin B7) is a water soluble B vitamin that functions as an essential cofactor for five carboxylase enzymes: acetyl CoA carboxylase (ACC1 and ACC2), propionyl CoA carboxylase (PCC), methylcrotonyl CoA carboxylase (MCC), and pyruvate carboxylase (PC). These enzymes are involved in fatty acid synthesis, amino acid catabolism, and gluconeogenesis respectively, making biotin a central cofactor in the metabolism of all three macronutrient classes: carbohydrates, fats, and proteins.

Biotin is water soluble and is not stored in significant amounts in the body, making consistent daily intake important. It is found in a variety of foods including egg yolks, liver, nuts, seeds, and legumes, though bioavailability varies. Biotin deficiency, while uncommon in healthy adults eating a varied diet, can occur in those consuming large amounts of raw egg whites (which contain avidin, a protein that binds and prevents biotin absorption), those with certain genetic disorders of biotin metabolism, and those on long term anticonvulsant therapy.

Biotin and Hair, Skin, and Nail Health

Biotin is commonly associated with hair, skin, and nail health in the supplement market. Keratin, the primary structural protein of hair, nails, and the outer layer of skin, is synthesized from amino acids whose metabolism depends in part on biotin dependent carboxylase enzyme activity. Biotin deficiency is associated with hair loss, skin rash, and brittle nails. However, the evidence for biotin supplementation improving hair, skin, or nail outcomes in individuals without biotin deficiency is limited. The licensed Health Canada claims for this formula are factor in the maintenance of good health and support for carbohydrate, fat, and protein metabolism.

Why 10,000mcg?

The recommended dietary allowance (RDA) for biotin in adults is 30mcg per day. Supplemental biotin is available in a wide range of doses from 100mcg to 10,000mcg and above. High dose biotin supplementation at 10,000mcg is commonly used in the hair, skin, and nail supplement category. Biotin is water soluble and excess amounts are excreted in urine, so toxicity from high dose supplementation has not been established. However, high dose biotin does carry a significant interaction with laboratory testing that must be considered.

Biotin and Laboratory Test Interference

High dose biotin supplementation can interfere with certain immunoassay based laboratory tests including thyroid function tests (TSH, T3, T4), cardiac troponin assays, vitamin D measurements, and hormone panels, potentially causing falsely elevated or falsely lowered results. This is a clinically significant interaction at 10,000mcg per day. Discontinue biotin supplementation at least 72 hours before any scheduled blood work and inform your healthcare practitioner that you are taking high dose biotin before any laboratory testing.

Medicinal Ingredient (per capsule)

• Biotin (Biotin) 10,000mcg Vitamin B7 | Factor in the maintenance of good health | Helps metabolize carbohydrates, fats, and proteins | NPN 80071632

Non medicinal ingredients: Magnesium stearate, hypromellose (vegetable capsule shell).

Quality and Trust

• NPN 80071632 Licensed by Health Canada as a Natural Health Product
• Made in Canada GMP certified facility under Health Canada oversight
• 10,000mcg biotin per capsule High potency vitamin B7
• Vegan capsule Hypromellose shell, no gelatin
• Non GMO | Gluten free | Soy free | Dairy free
• 60 capsules 60 day supply at 1 capsule per day

Who This Is For

• Adults seeking high potency biotin (vitamin B7) as a factor in the maintenance of good health and to support carbohydrate, fat, and protein metabolism
• Those who prefer a clean, vegan, non GMO, Canadian made biotin supplement
• Adults who understand the 4 week duration of use restriction and the biotin laboratory test interference consideration at 10,000mcg

How to Use

Adults: Take 1 capsule once daily. At 1 capsule per day, one bottle of 60 capsules provides a 60 day supply. Consult a healthcare practitioner for use beyond 4 weeks. Discontinue biotin supplementation at least 72 hours before any scheduled blood work and inform your healthcare practitioner.